MyBioSource.com's Anti-gamma Catenin antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Western Blot. The Anti-gamma Catenin antibody was generated using junction plakoglobin, JUP, PDGB, and plakoglobin as the antigen and it reacts with Human, Mouse, and Rat.
Description
Description: Rabbit IgG polyclonal antibody for Junction plakoglobin(JUP) detection. Tested with WB in Human, Mouse, Rat.
Background: Cateningamma, also known as junction plakoglobin(JUP) or plakoglobin(PKGB). Plakoglobin is a major cytoplasmic protein which is the only known constituent common to submembranous plaques of both desmosomes and intermediate junctions. Cateninbeta and cateningamma(plakoglobin), vertebrate homologs of Drosophila armadillo, function in cell adhesion and the Wnt signaling pathway. Cateningamma may have distinct roles in Wnt signaling and cancer via differential effects on downstream target genes